Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | HSPB1 | P04792 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | USP10 | Q14694 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385912 | 1.00 | TDP1 (1.00) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| SCHEMBL31121788 | 0.98 | TDP1 (0.96) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| Methyl Alcohol SCHEMBL29115301 | 0.94 | ATM (0.88) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| Acetonitrile SCHEMBL28605591 | 0.89 | TDP1 (0.79) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| SCHEMBL21994357 | 0.86 | TDP1 (0.73) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| SCHEMBL27739457 | 0.86 | TDP1 (0.73) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| SCHEMBL29745239 | 0.84 | TDP1 (0.72) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| SCHEMBL216553 | 0.84 | TDP1 (0.72) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| SCHEMBL17749477 | 0.84 | TDP1 (0.71) | TDP1ATMHSPB1ALDH1A1HIF1A | |
| SCHEMBL102780 | 0.82 | ATM (0.69) | TDP1ATMHSPB1ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2793 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344302-A | Preparation method of flumioxazin intermediate | 北京颖泰嘉和生物科技股份有限公司 | 2024-07-16 | — | — | CN | claimed |
| US-20240207381-A1 | BIHAPTENIZED AUTOLOGOUS VACCINES AND USES THEREOF | BIOVAXYS INC (US) | 2024-06-27 | — | — | US | claimed |
| CN-118179542-A | Carbon-based catalyst, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118139495-A | Preparation method of doped hole transport layer, photovoltaic cell and preparation method thereof | 四川恒立聚能光电科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-116082325-B | Benzoxazinone compound containing isoxazole heterocycle, and preparation method and application thereof | 浙江工业大学 | 2024-04-16 | — | — | CN | claimed |
| CN-117705963-A | Method for detecting related substances in 2, 4-difluoronitrobenzene | 南京一诺医药科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-114621097-B | Method for preparing 2, 4-difluoroaniline by catalytic hydrogenation of 2, 4-difluoronitrobenzene | 浙江解氏新材料股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117658885-A | Benzyloxy aryl compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | claimed |
| EP-4329779-A1 | BIHAPTENIZED AUTOLOGOUS VACCINES AND USES THEREOF | BioVaxys Inc. (US) | 2024-03-06 | — | — | EP | claimed |
| CN-113929582-B | Synthesis method of 2- (5-fluoro-2-nitrophenoxy) acetate | 山东京博农化科技股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| EP-0537592-A1 | Process for the preparation of 2-nitro-5-fluoro- respectively -5-chloro-phenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | claimed |
| EP-0243000-B1 | POLYCYANOARYL ETHER, METHOD FOR PREPARING THE SAME AND USES THEREOF | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-10-03 | — | — | EP | claimed |
| EP-0243000-A1 | Polycyanoaryl ether, method for preparing the same and uses thereof | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-10-28 | — | — | EP | claimed |
| US-4642399-A | REACTION OF CHLORONITRO BENZENE COMPOUNDS WITH FLUORIDE SALT | MALLINCKRODT, INC. (US) | 1987-02-10 | — | — | US | claimed |
| EP-0032620-B2 | Process for preparing therapeutic 2-arylpropionic acids and esters, and novel arylmethylmalonate esters | THE UPJOHN COMPANY (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0032620-B1 | Process for preparing therapeutic 2-arylpropionic acids and esters, and novel arylmethylmalonate esters | THE UPJOHN COMPANY (US) | 1984-05-30 | — | — | EP | claimed |
| US-4418229-A | DISPLACEMENT OF CHLORONITROBENZENES WITH A FLUORIDE SALT, QUATERNARY AMMONIUM PHASE TRANSFER CATALYSTS | MALLINCKRODT, INC. (US) | 1983-11-29 | — | — | US | claimed |
| EP-0032620-A1 | Process for preparing therapeutic 2-arylpropionic acids and esters, and novel arylmethylmalonate esters | THE UPJOHN COMPANY (US) | 1981-07-29 | — | — | EP | claimed |
| EP-0001427-B1 | 2,6-DICHLORO-3'-FLUORO-4-TRIFLUOROMETHYL-6'-NITRODIPHENYL ETHER, A PROCESS FOR ITS PREPARATION AND ITS APPLICATION AS A DEFOLIATION AGENT FOR COTTON | BAYER AG (DE) | 1980-09-17 | — | — | EP | claimed |
| EP-0001427-A1 | 2,6-Dichloro-3'-fluoro-4-trifluoromethyl-6'-nitrodiphenyl ether, a process for its preparation and its application as a defoliation agent for cotton | BAYER AG (DE) | 1979-04-18 | — | — | EP | claimed |