Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848464 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAKMT2AMEN1NPC1 | |
| SCHEMBL4845951 | 0.90 | MAPT (0.43) | SMN1; SMN2GAATHRBL3MBTL1MAPT | |
| SCHEMBL4856854 | 0.90 | MAPT (0.54) | SMN1; SMN2GAAKMT2AMEN1NPC1 | |
| SCHEMBL4845948 | 0.90 | MAPT (0.43) | SMN1; SMN2GAATHRBL3MBTL1MAPT | |
| SCHEMBL4856844 | 0.90 | MAPT (0.54) | SMN1; SMN2GAAKMT2AMEN1NPC1 | |
| SCHEMBL4855188 | 0.89 | MAPT (0.42) | SMN1; SMN2GAAKMT2AMEN1THRB | |
| SCHEMBL4853490 | 0.89 | MAPT (0.42) | SMN1; SMN2GAAKMT2AMEN1NPC1 | |
| SCHEMBL4853481 | 0.89 | MAPT (0.42) | SMN1; SMN2GAAKMT2AMEN1NPC1 | |
| SCHEMBL4855193 | 0.89 | MAPT (0.42) | SMN1; SMN2GAAKMT2AMEN1THRB | |
| SCHEMBL4852578 | 0.88 | MAPT (0.42) | SMN1; SMN2GAAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724275-B1 | PROCESS FOR PRODUCING AMINOPHOSPHONIC ACID DERIVATIVE | JAPAN SCIENCE & TECH AGENCY (JP) | 2015-04-08 | — | — | EP | disclosed |
| EP-1724275-A1 | PROCESS FOR PRODUCING AMINOPHOSPHONIC ACID DERIVATIVE | Japan Science and Technology Agency (JP) | 2006-11-22 | — | — | EP | disclosed |