Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14144999 | 0.86 | POLB (0.53) | ATMPOLBMAPTKMT2ACA2 | |
| SCHEMBL7435099 | 0.85 | ATM (0.76) | ATMPOLBMAPTKMT2ACA2 | |
| SCHEMBL14144990 | 0.84 | POLB (0.51) | ATMPOLBMAPTKMT2ACA2 | |
| SCHEMBL13116257 | 0.84 | CYP1A2 (0.63) | ATMPOLBMAPTKMT2ALMNA | |
| SCHEMBL15684920 | 0.83 | GAA (0.54) | ATMPOLBMAPTKMT2ACA2 | |
| SCHEMBL17833768 | 0.83 | KDM4E (0.66) | KMT2ASMN1; SMN2KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11808765 | 0.83 | ATM (0.73) | ATMPOLBMAPTKMT2ACA2 | |
| SCHEMBL30230461 | 0.83 | ATM (1.00) | ATMPOLBMAPTKMT2ACA2 | |
| SCHEMBL8635081 | 0.83 | ATM (1.00) | ATMPOLBMAPTKMT2ACA2 | |
| SCHEMBL557799 | 0.83 | ATM (1.00) | ATMPOLBMAPTKMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725517-A2 | PROCESS FOR THE PREPARATION OF FENOLDOPAM MESYLATE | Sicor Inc. (US) | 2006-11-29 | — | — | EP | disclosed |
| US-20060194967-A1 | Process for the preparation of Fenoldopam Mesylate | SICOR, INC. | 2006-08-31 | — | — | US | disclosed |
| WO-2006079090-A2 | PROCESS FOR THE PREPARATION OF FENOLDOPAM MESYLATE | SICOR INC. (US) | 2006-07-27 | — | — | WO | disclosed |
| EP-0127423-B1 | 1-(4'-BRANCHED ALKYLSULFONYLPHENYL)-6-CHLORO-7,8-DIHYDROXY-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES | SMITHKLINE BECKMAN CORPORATION (US) | 1988-02-03 | — | — | EP | disclosed |
| US-4514394-A | Anti-hypertensive use of 1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines | SMITHKLINE BECKMAN CORPORATION (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0127423-A2 | 1-(4'-Branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines | SMITHKLINE BECKMAN CORPORATION (US) | 1984-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194967-A1 | Process for the preparation of Fenoldopam Mesylate | TPMT, COMT, CYP4F3 | ATM 3555/4885POLB 414/4885MAPT 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.