Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 15/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713132 | 1.00 | DPP7 (0.48) | DPP7DPP4DPP8DPP9ITGB3 | |
| Hydrochloric Acid SCHEMBL6767883 | 0.99 | DPP7 (0.47) | DPP7DPP4DPP8DPP9ITGB3 | |
| Hydrochloric Acid SCHEMBL6767887 | 0.99 | DPP7 (0.47) | DPP7DPP4DPP8DPP9ITGB3 | |
| SCHEMBL6763864 | 0.96 | DPP7 (0.47) | DPP7DPP4DPP8DPP9ITGB3 | |
| SCHEMBL7293680 | 0.96 | DPP7 (0.47) | DPP7DPP4DPP8DPP9ITGB3 | |
| SCHEMBL7298630 | 0.91 | DPP7 (0.50) | DPP7DPP4DPP8 | |
| SCHEMBL7298625 | 0.91 | DPP7 (0.50) | DPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6768443 | 0.90 | DPP7 (0.49) | DPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6768444 | 0.90 | DPP7 (0.49) | DPP7DPP4DPP8 | |
| SCHEMBL7301373 | 0.87 | DPP7 (0.40) | DPP7DPP4DPP8DPP9ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-B1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | SERVIER LAB (FR) | 2006-01-18 | — | — | EP | disclosed |
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |