Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713453 | 0.95 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL5713488 | 0.92 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL5713456 | 0.92 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL5713446 | 0.90 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL5713473 | 0.89 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL5713505 | 0.87 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL3049355 | 0.87 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL3056366 | 0.87 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL5713450 | 0.86 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL5713476 | 0.86 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450797-B1 | BENZOTHIAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-06-21 | — | — | EP | claimed |