Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15347753 | 0.84 | BDKRB1 (0.63) | BDKRB1 | |
| SCHEMBL12010215 | 0.78 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL12730899 | 0.78 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL10044350 | 0.78 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL10044361 | 0.78 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL571391 | 0.78 | BDKRB1 (1.00) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL15347598 | 0.77 | BDKRB1 (0.98) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL15347819 | 0.77 | BDKRB1 (0.98) | BDKRB1 | |
| SCHEMBL4000589 | 0.77 | BDKRB1 (0.93) | BDKRB1 | |
| SCHEMBL12731604 | 0.76 | BDKRB1 (0.95) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601181-A1 | ACID ADDITION SALTS OF THE 2-[2-[[(4-METHOXY-2,6-DIMETHYLPHENYL)SULFONYL]-(METHYL)AMINO]ETHOXY]-N-METHYL-N-[3-(4-METHYLPIPERAZIN-1-YL)CYCLOHEXYL]ACETAMIDE AND THE USE THEREOF AS BRADYKININ B1 RECEPTOR ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017027-A1 | ACID ADDITION SALTS OF THE 2-[2-[[(4-METHOXY-2,6-DIMETHYLPHENYL)SULFONYL]-(METHYL)AMINO]ETHOXY]-N-METHYL-N-[3-(4-METHYLPIPERAZIN-1-YL)CYCLOHEXYL] ACETAMIDE AND THE USE THEREOF AS BRADYKININ B1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |