Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099779 | 0.90 | PTPN1 (0.48) | PTPN1MAOBMAOAMIFMEN1 | |
| SCHEMBL28316491 | 0.86 | PTPN1 (0.48) | PTPN1MAOBMAOAMEN1KMT2A | |
| SCHEMBL28636824 | 0.85 | MIF (0.41) | PTPN1MAOBMAOAMIFMEN1 | |
| SCHEMBL6498085 | 0.78 | PTPN1 (0.48) | PTPN1MAOBMIFMEN1KMT2A | |
| SCHEMBL38664154 | 0.73 | CYP19A1 (0.40) | PTPN1MAOBMAOACISD1MIF | |
| SCHEMBL1500180 | 0.71 | MAOB (0.50) | PTPN1MAOBMAOAMIFMAPT | |
| SCHEMBL30251200 | 0.71 | MAOB (0.50) | PTPN1MAOBMAOAMIFMAPT | |
| SCHEMBL29036854 | 0.70 | MIF (0.44) | PTPN1MAOBMAOACISD1MIF | |
| (3R)-4'-Methoxy-2',3',7-Trihydroxyisoflavanone SCHEMBL30217561 | 0.70 | PTPN1 (0.61) | PTPN1MAOBMAOAMEN1KMT2A | |
| (3R)-4'-Methoxy-2',3',7-Trihydroxyisoflavanone SCHEMBL17963716 | 0.70 | PTPN1 (0.61) | PTPN1MAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598150-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | The Hospital For Sick Children (CA) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012018643-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2012-02-09 | — | — | WO | disclosed |
| WO-2010039679-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2010-04-08 | — | — | WO | disclosed |