Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434688 | 0.86 | TSHR (0.53) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31747006 | 0.86 | TSHR (0.54) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL713941 | 0.86 | TSHR (0.54) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21412681 | 0.84 | MAPT (0.50) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10608137 | 0.84 | TSHR (0.58) | TSHRMAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL27791672 | 0.83 | MAPT (0.49) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8790409 | 0.82 | TSHR (0.55) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18138464 | 0.80 | MAPT (0.53) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13344094 | 0.80 | MAPT (0.53) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23093075 | 0.80 | MAPT (0.46) | TSHRMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050547-A1 | MITOCHONDRIAL COMPLEX I INHIBITORS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-03-18 | — | — | WO | disclosed |
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |