SCHEMBL5718052

SCHEMBL5718052

CCN(CCO)C(=O)N(Cc1ccc(C2CCCCC2)cc1)c1ccc(F)cc1.NC(=O)[C@@H](NC(=O)O)c1ccc(F)cc1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 19/20 0.39
GCGR P47871 1/20 0.37
GIPR P48546 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5718059 0.91 STAT3 (0.40) STAT3GCGRGIPR
Bicarbonate SCHEMBL5718168 0.87 STAT3 (0.46) STAT3
SCHEMBL5718048 0.85 PRCP (0.36)
SCHEMBL5717966 0.79 FFAR4 (0.41)
Bicarbonate SCHEMBL5718071 0.78 STAT3 (0.46) STAT3
SCHEMBL5717936 0.78 STAT3 (0.43) STAT3GCGRGIPR
SCHEMBL5717933 0.76 SMN1; SMN2 (0.45) STAT3
SCHEMBL5846941 0.76 GAA (0.40) STAT3
SCHEMBL5718166 0.76 GAA (0.40) STAT3
SCHEMBL5718198 0.74 FFAR4 (0.41) STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1318977-B1 SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF BAYER HEALTHCARE AG (DE) 2006-12-06 EP claimed
EP-1318977-B1 SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF BAYER HEALTHCARE AG (DE) 2006-12-06 EP disclosed