Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | SMG1 | Q96Q15 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358064 | 0.84 | PIK3CA (0.54) | PIK3CALRRK2PIK3CBOGASMG1 | |
| SCHEMBL3742630 | 0.84 | PIK3CA (0.57) | PIK3CALRRK2PIK3CBABL1KMO | |
| SCHEMBL8197483 | 0.84 | PIK3CA (0.59) | PIK3CALRRK2PIK3CBOGASMG1 | |
| SCHEMBL2459118 | 0.84 | PIK3CA (0.54) | PIK3CALRRK2PIK3CBOGASMG1 | |
| SCHEMBL13069962 | 0.81 | PIK3CA (0.53) | PIK3CALRRK2PIK3CBOGASMG1 | |
| SCHEMBL8228263 | 0.80 | LRRK2 (0.56) | PIK3CALRRK2PIK3CBOGAOPRM1 | |
| SCHEMBL10154083 | 0.80 | PIK3CA (0.50) | PIK3CALRRK2PIK3CBOGASMG1 | |
| SCHEMBL13028832 | 0.80 | PIK3CA (0.50) | PIK3CALRRK2PIK3CBOGASMG1 | |
| SCHEMBL10210050 | 0.80 | PIK3CA (0.50) | PIK3CALRRK2PIK3CBOGASMG1 | |
| SCHEMBL1886526 | 0.78 | PIK3CA (0.58) | PIK3CASMN1; SMN2OPRM1OPRL1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | Leo Pharma A/S (DK) | 2006-09-06 | — | — | EP | disclosed |
| EP-1444205-B1 | METHOD FOR PRODUCING 2-HALOGEN-PYRIDINE-CARBOXYLIC ACID AMIDES | BASF AG (DE) | 2006-02-01 | — | — | EP | disclosed |
| WO-2005054179-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2005-06-16 | — | — | WO | disclosed |