Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.36 |
| ▸ | FLT1 | P17948 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714430 | 0.91 | KIT (0.43) | MEN1KMT2AL3MBTL1PDE5ASCN9A | |
| SCHEMBL5718662 | 0.85 | PDE5A (0.43) | PDE5AKDRFLT1 | |
| SCHEMBL1715778 | 0.84 | KDR (0.53) | KDRFLT1P2RX7 | |
| SCHEMBL1715441 | 0.80 | KDM4C (0.48) | PDE5ASCN9AKDRFLT1KDM4E | |
| SCHEMBL1715297 | 0.80 | KDR (0.45) | SCN9AKDRFLT1GSK3BALDH1A1 | |
| SCHEMBL1715142 | 0.80 | KDR (0.43) | SCN9AKDRFLT1GSK3AGSK3B | |
| SCHEMBL1715615 | 0.78 | POLB (0.44) | PDE5AKDRFLT1NAMPTALDH1A1 | |
| SCHEMBL1714589 | 0.78 | KDR (0.43) | KMT2AL3MBTL1SCN9AKDRFLT1 | |
| SCHEMBL1714601 | 0.78 | NPC1 (0.50) | MEN1KMT2AL3MBTL1KDRFLT1 | |
| SCHEMBL5718686 | 0.77 | POLB (0.39) | KMT2AL3MBTL1KDRFLT1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | Leo Pharma A/S (DK) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054179-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2005-06-16 | — | — | WO | disclosed |