Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718782 | 1.00 | SRC (0.55) | SRCTRPV1KMT2APTPN1BACE1 | |
| SCHEMBL17627685 | 0.91 | SRC (0.59) | SRCTRPV1PTPN1STAT3ALDH1A1 | |
| SCHEMBL309480 | 0.91 | SRC (0.59) | SRCTRPV1PTPN1STAT3ALDH1A1 | |
| SCHEMBL156333 | 0.91 | SRC (0.59) | SRCTRPV1PTPN1STAT3ALDH1A1 | |
| SCHEMBL29558348 | 0.83 | SRC (0.48) | SRCPTPN1STAT3 | |
| SCHEMBL17785040 | 0.83 | SRC (0.48) | SRCPTPN1STAT3 | |
| SCHEMBL17785039 | 0.83 | SRC (0.48) | SRCPTPN1STAT3 | |
| SCHEMBL30091075 | 0.83 | SRC (0.48) | SRCPTPN1STAT3 | |
| SCHEMBL12500490 | 0.83 | SRC (0.48) | SRCPTPN1STAT3 | |
| SCHEMBL1834290 | 0.83 | SRC (0.48) | SRCPTPN1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185178-B1 | INSECTICIDAL COMPOSITIONS | HERBAL SCIENCES INTERNAT LTD (GB) | 2006-10-25 | — | — | EP | disclosed |
| EP-1185178-A2 | INSECTICIDAL COMPOSITIONS | Wilkinson, John Alfred (GB) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000064265-A2 | INSECTICIDAL COMPOSITIONS | WILKINSON JOHN ALFRED (GB) | 2000-11-02 | — | — | WO | disclosed |