Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5719137 | 0.92 | DPP4 (0.66) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555644 | 0.88 | DPP4 (0.71) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL5719462 | 0.87 | DPP4 (0.60) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL5719515 | 0.86 | DPP4 (0.60) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL5718865 | 0.86 | DPP4 (0.59) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL5718799 | 0.86 | DPP4 (0.59) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL5719440 | 0.86 | DPP4 (0.59) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL5719079 | 0.86 | DPP4 (0.74) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL6688447 | 0.85 | DPP4 (0.71) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL5719052 | 0.85 | DPP4 (0.71) | DPP4CHRM1CHRM2CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | DPP4 1/4885CHRM1 669/4885CHRM2 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.