Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.77 |
| ▸ | FAP | Q12884 | 5/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6689940 | 0.94 | DPP4 (0.69) | DPP4FAPDPP9L3MBTL1 | |
| SCHEMBL5719456 | 0.92 | DPP4 (0.77) | DPP4FAPDPP9 | |
| SCHEMBL5719286 | 0.91 | DPP4 (0.76) | DPP4FAPDPP9L3MBTL1 | |
| SCHEMBL5719225 | 0.89 | DPP4 (0.73) | DPP4FAPDPP9L3MBTL1 | |
| SCHEMBL5718795 | 0.89 | DPP4 (0.73) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5718973 | 0.88 | DPP4 (0.74) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL5719250 | 0.87 | DPP4 (0.83) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL5275960 | 0.87 | DPP4 (1.00) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5719224 | 0.87 | DPP4 (0.67) | DPP4FAPDPP9L3MBTL1 | |
| SCHEMBL5719078 | 0.86 | DPP4 (0.82) | DPP4FAPDPP9L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | claimed |