Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.59 |
| ▸ | FAP | Q12884 | 5/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719212 | 0.91 | DPP4 (0.57) | DPP4FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL5718899 | 0.90 | DPP4 (0.57) | DPP4FAPDPP9ALDH1A1SMN1; SMN2 | |
| SCHEMBL5719236 | 0.89 | DPP4 (0.59) | DPP4FAPDPP9ALDH1A1SMN1; SMN2 | |
| SCHEMBL5719433 | 0.89 | DPP4 (0.74) | DPP4FAPDPP9ALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5719303 | 0.88 | DPP4 (0.51) | DPP4FAPDPP9ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5719306 | 0.87 | DPP4 (0.64) | DPP4FAPDPP9ALDH1A1SMN1; SMN2 | |
| SCHEMBL5719438 | 0.87 | DPP4 (0.74) | DPP4FAPDPP9ALDH1A1SMN1; SMN2 | |
| SCHEMBL5719456 | 0.87 | DPP4 (0.77) | DPP4FAPDPP9CHRM1 | |
| Trifluoroacetic Acid SCHEMBL5718825 | 0.86 | DPP4 (0.51) | DPP4FAPDPP9ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5719516 | 0.85 | DPP4 (0.64) | DPP4FAPDPP9ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | claimed |