Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652577 | 0.90 | BCL2L1 (0.56) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL4652440 | 0.89 | BCL2L1 (0.58) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL4651677 | 0.89 | BCL2L1 (0.58) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL4652522 | 0.87 | BCL2L1 (0.61) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL14066554 | 0.87 | BCL2L1 (0.56) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL14066701 | 0.87 | BCL2L1 (0.55) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL4652272 | 0.86 | BCL2L1 (0.62) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL4652402 | 0.85 | BCL2L1 (0.65) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL14066628 | 0.84 | BCL2L1 (0.57) | BCL2L1TP53MDM2MCL1PDE1A | |
| SCHEMBL14066613 | 0.84 | BCL2L1 (0.56) | BCL2L1TP53MDM2MCL1PDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408986-A4 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2006-01-11 | — | — | EP | disclosed |
| EP-1408986-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002089738-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2002-11-14 | — | — | WO | disclosed |