⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12004411 | 0.67 | — | — | |
| SCHEMBL1149316 | 0.67 | — | — | |
| SCHEMBL10579614 | 0.60 | — | — | |
| SCHEMBL702020 | 0.59 | — | — | |
| SCHEMBL16732706 | 0.59 | — | — | |
| SCHEMBL38028 | 0.59 | — | — | |
| SCHEMBL67739 | 0.59 | — | — | |
| SCHEMBL2136306 | 0.59 | — | — | |
| SCHEMBL18248130 | 0.58 | — | — | |
| SCHEMBL73273 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002388-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | CHINA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH CO., LTD. (CN) | 2023-01-05 | — | — | US | claimed |
| US-11420970-B1 | Piperidinyl-methyl-purineamines as NSD2 inhibitors and anti-cancer agents | NOVARTIS AG (CH) | 2022-08-23 | — | — | US | claimed |
| EP-4013755-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | Novartis AG (CH) | 2022-06-22 | — | — | EP | claimed |
| WO-2021028854-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | claimed |
| WO-2021026803-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | claimed |
| CN-110023302-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-105980353-B | ROR gamma modulators | 领先制药控股公司 | 2019-06-14 | — | — | CN | claimed |
| CN-109715617-A | Dimethoxyphenyl-substituted indole compounds as inhibitors of TLR7, TLR8 or TLR9 | 百时美施贵宝公司 | 2019-05-03 | — | — | CN | claimed |
| CN-105189508-B | Naphthenic base nitrile Pyrazolopyridine ketone as JANUS kinase inhibitor | 默沙东公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108884050-A | Tetrahydroisoquinoline derivatives | UCB生物制药私人有限公司 | 2018-11-23 | — | — | CN | claimed |
| EP-0639195-B1 | 2-ACYLOXYCEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN SPA (IT) | 1999-05-26 | — | — | EP | claimed |
| US-5587373-A | ELASTASE INHIBITORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-12-24 | — | — | US | claimed |
| EP-0337704-B1 | Beta-lactam derivatives | PHARMACIA SPA (IT) | 1995-06-14 | — | — | EP | claimed |
| EP-0639195-A1 | 2-ACYLOXYCEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1995-02-22 | — | — | EP | claimed |
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | claimed |
| WO-1994020504-A1 | 2-ACYLOXYCEPHEM DERIVATIVES AS ELASTASE INHIBITORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-09-15 | — | — | WO | claimed |
| EP-0505413-A1 | BETA-LACTAM DERIVATIVES. | ERBA FARMITALIA (IT) | 1992-09-30 | — | — | EP | claimed |
| US-5077286-A | Human leukocyte elastase inhibitor | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-12-31 | — | — | US | claimed |
| WO-1991009036-A1 | BETA-LACTAM DERIVATIVES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-06-27 | — | — | WO | claimed |
| EP-0337704-A2 | Beta-lactam derivatives | PHARMACIA S.p.A. (IT) | 1989-10-18 | — | — | EP | claimed |