SCHEMBL5720895

SCHEMBL5720895

CC(C)N(C)C(C)c1ccc(N2CCC(NS(=O)(=O)c3ccc4ccccc4c3)C2=O)c(F)c1

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5386434 0.92 F10 (1.00) F10
SCHEMBL5395896 0.86 F10 (1.00) F10
SCHEMBL5370499 0.86 F10 (1.00) F10
SCHEMBL5375578 0.86 F10 (1.00) F10
SCHEMBL5371156 0.83 F10 (1.00) F10
SCHEMBL5371155 0.81 F10 (0.82) F10
SCHEMBL5377816 0.81 F10 (0.82) F10
SCHEMBL5395727 0.79 F10 (1.00) F10
SCHEMBL5395805 0.79 F10 (1.00) F10
SCHEMBL5370548 0.79 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1641752-A1 3- SULFONYLAMINO- PYRROLIDINE- 2- ONE DERIVATIVES AS INHIBITORS OF FACTOR XA GLAXO GROUP LIMITED (GB) 2006-04-05 EP claimed
WO-2004110997-A1 3- SULFONYLAMINO- PYRROLIDINE- 2- ONE DERIVATIVES AS INHIBITORS OF FACTOR XA GLAXO GROUP LIMITED (GB) 2004-12-23 WO claimed