Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 1.00 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | MELK | Q14680 | 1/20 | 0.48 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365341 | 1.00 | PARP1 (1.00) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| SCHEMBL27946369 | 0.98 | PARP1 (0.95) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL30294983 | 0.98 | PARP1 (0.95) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL7005886 | 0.98 | PARP1 (0.95) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| Potassium SCHEMBL3099047 | 0.98 | PARP1 (0.95) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| Benzene SCHEMBL670928 | 0.98 | PARP1 (0.95) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL2455495 | 0.98 | PARP1 (0.95) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| SCHEMBL670718 | 0.98 | PARP1 (0.95) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL7380702 | 0.98 | PARP1 (0.95) | PARP1GRM5ALDH1A1HSD17B10TDP1 | |
| Ethyne SCHEMBL16616798 | 0.96 | PARP1 (0.91) | PARP1GRM5ALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6910 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125346-A1 | Isoquinolinone Derivatives and 4H-Quinolizinone Derivatives and Pharmaceutical Compositions Thereof for the Treatment of Disease | BEONE MEDICINES I GMBH (CH) | 2026-05-07 | — | — | US | claimed |
| EP-4592399-B1 | COMPOSITIONS, KITS AND METHODS FOR ISOLATING TARGET POLYNUCLEOTIDES | DNAE DIAGNOSTICS LTD (GB) | 2026-03-11 | — | — | EP | claimed |
| EP-4396191-B1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2026-02-18 | — | — | EP | claimed |
| US-20250388599-A1 | TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2025-12-25 | — | — | US | claimed |
| EP-4653437-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Innovo Therapeutics Inc. (KR) | 2025-11-26 | — | — | EP | claimed |
| US-12448389-B2 | BRM targeting compounds and associated methods of use | PRELUDE THERAPEUTICS INCORPORATED (US) | 2025-10-21 | — | — | US | claimed |
| EP-4611899-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | claimed |
| US-20250241965-A1 | METHOD TO IMPROVE CELL VIABILITY OF CARDIOMYOCYTES | UNIVERSITY OF WASHINGTON (US) | 2025-07-31 | — | — | US | claimed |
| US-20250170121-A1 | ISOQUINOLINONE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR | FUDAN UNIVERSITY (CN) | 2025-05-29 | — | — | US | claimed |
| WO-2025076059-A1 | ROCAGLATE DERIVATIVES AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-04-10 | — | — | WO | claimed |
| EP-0113910-B1 | ISOCARBOSTYRIL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-10-11 | — | — | EP | claimed |
| EP-0326386-A2 | Isoquinolinones | MAY & BAKER LIMITED (GB) | 1989-08-02 | — | — | EP | claimed |
| EP-0165110-B1 | OPTICALLY ACTIVE ISOCARBOSTYRIL DERIVATIVES AND A METHOD OF PREPARING THE SAME | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-12-28 | — | — | EP | claimed |
| US-4659833-A | FOUR OPTICAL ISOMERS OF 1-(2'-(O-METHOXYPHENYL)-1'-METHYLETHYLAMINO)-3-(4\"-ISOCARBOSTYRILOXY)-2 -PROPANOL ISOLATED BY LIQUID CHROMATOGRAPHY | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1987-04-21 | — | — | US | claimed |
| US-4656278-A | Isoquinoline derivatives and their preparation | SYNTHELABO (FR) | 1987-04-07 | — | — | US | claimed |
| EP-0165110-A1 | Optically active isocarbostyril derivatives and a method of preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1985-12-18 | — | — | EP | claimed |
| EP-0113910-A1 | Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1984-07-25 | — | — | EP | claimed |
| US-4443607-A | ANTIULCER, HYPOTENSIVE, ANALGESIC, ANTIHISTAMINE, ANTICHOLINERGIC- ANTISECRETORY, BLOOD FLOW | MARUKO SEIYAKU CO., LTD. (JP) | 1984-04-17 | — | — | US | claimed |
| EP-0064294-A1 | 1,5-Substituted isoquinoline derivatives | G.D. Searle & Co. (US) | 1982-11-10 | — | — | EP | claimed |
| US-4198512-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-04-15 | — | — | US | claimed |