Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | PPARD | Q03181 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963793 | 0.99 | TSHR (0.54) | TSHRRECQLPPARAPPARGPPARD | |
| SCHEMBL5361731 | 0.99 | TSHR (0.54) | TSHRRECQLPPARAPPARGPPARD | |
| SCHEMBL5353330 | 0.99 | TSHR (0.54) | TSHRRECQLPPARAPPARGPPARD | |
| SCHEMBL3963046 | 0.99 | TSHR (0.54) | TSHRRECQLPPARAPPARGPPARD | |
| SCHEMBL5024521 | 0.85 | PTPN1 (0.60) | PPARAPPARGPPARDKDM4EPTPN1 | |
| SCHEMBL5027084 | 0.85 | PTPN1 (0.60) | PPARAPPARGPPARDKDM4EPTPN1 | |
| SCHEMBL5024583 | 0.85 | PTPN1 (0.60) | PPARAPPARGPPARDKDM4EPTPN1 | |
| SCHEMBL3960340 | 0.85 | SMN1; SMN2 (0.60) | PPARAPPARGPPARDKDM4EPTPN1 | |
| SCHEMBL3960334 | 0.85 | SMN1; SMN2 (0.60) | PPARAPPARGPPARDKDM4EPTPN1 | |
| SCHEMBL6148812 | 0.84 | PTPN1 (0.68) | PPARAPPARGPPARDKDM4EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675820-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | AstraZeneca AB (SE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2004113270-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | disclosed |