SCHEMBL5721786

SCHEMBL5721786

CCCC1=Cc2c(ccc(C)c2-c2ccccc2CC)C1[Zr](Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
CSNK2A3 Q8NEV1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721310 0.93 ELANE (0.31)
SCHEMBL5721282 0.89 HEXA (0.32)
SCHEMBL5721324 0.87 MDM2 (0.33)
SCHEMBL5721758 0.86 CSNK2A2 (0.32) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL5721337 0.86 PDCD1 (0.31)
SCHEMBL5721270 0.86
SCHEMBL5721951 0.86 ELANE (0.31)
SCHEMBL5721608 0.85
SCHEMBL5721254 0.85
SCHEMBL5721531 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed