Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | ALPG | P10696 | 5/20 | 0.46 |
| ▸ | PLAA | Q9Y263 | 3/20 | 0.46 |
| ▸ | ALPL | P05186 | 3/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722000 | 0.89 | ALPG (0.45) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5721975 | 0.89 | CA12 (0.51) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5721969 | 0.89 | CA12 (0.53) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5721949 | 0.85 | CA12 (0.54) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5721917 | 0.81 | ALPG (0.46) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5722026 | 0.79 | CA12 (0.73) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5721986 | 0.78 | ALPG (0.47) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5722027 | 0.77 | ALPG (0.49) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5722116 | 0.77 | CA12 (0.55) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5722028 | 0.76 | ALPG (0.50) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554253-A4 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-09-20 | — | — | EP | disclosed |
| EP-1554253-A1 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2003101970-A1 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |