SCHEMBL5722211

SCHEMBL5722211

CC(C)NC(=O)N(C(=O)NC(C)C)c1ccc(S(=O)(=O)NCc2ccc3c(c2)nc(C(C)(F)F)n3CC2CCOCC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.50
CNR1 P21554 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4966401 0.88 CNR2 (0.52) CNR2CNR1
SCHEMBL14116550 0.84 CNR2 (0.51) CNR2CNR1
SCHEMBL4966519 0.78 CNR2 (0.51) CNR2CNR1
SCHEMBL5722219 0.77 CNR2 (0.65) CNR2CNR1
SCHEMBL4973284 0.77 CNR2 (0.61) CNR2CNR1
SCHEMBL5521048 0.76 CNR2 (0.62) CNR2CNR1
SCHEMBL5722227 0.75 CNR2 (0.56) CNR2CNR1
SCHEMBL1608880 0.73 CNR2 (0.68) CNR2CNR1
SCHEMBL4965890 0.73 CNR2 (0.51) CNR2CNR1
SCHEMBL4967473 0.73 CNR2 (0.56) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673369-A1 BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF AstraZeneca AB (SE) 2006-06-28 EP disclosed
WO-2005030761-A1 BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF ASTRAZENECA AB (SE) 2005-04-07 WO disclosed