Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722359 | 1.00 | ADRB3 (0.52) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5722314 | 0.90 | ADRB3 (0.59) | ADRB3ADRB1ADRB2 | |
| SCHEMBL13550993 | 0.90 | ADRB3 (0.59) | ADRB3ADRB1ADRB2 | |
| SCHEMBL1593170 | 0.90 | ADRB3 (0.59) | ADRB3ADRB1ADRB2 | |
| SCHEMBL1593171 | 0.90 | ADRB3 (0.59) | ADRB3ADRB1ADRB2 | |
| SCHEMBL3828053 | 0.90 | ADRB3 (0.59) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5722261 | 0.90 | ADRB3 (0.52) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5722259 | 0.90 | ADRB3 (0.52) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL5722281 | 0.89 | ADRB3 (0.58) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL5722313 | 0.89 | ADRB3 (0.58) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893432-B1 | PHENYLETHANOLAMINOTETRALINCARBOXAMIDE DERIVATIVES | KISSEI PHARMACEUTICAL (JP) | 2006-11-08 | — | — | EP | disclosed |
| US-6046192-A | Phenylethanolaminotetralincarboxamide derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0893432-A1 | PHENYLETHANOLAMINOTETRALINCARBOXAMIDE DERIVATIVES | Kissei Pharmaceutical Co. Ltd. (JP) | 1999-01-27 | — | — | EP | disclosed |