Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 6/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.49 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.49 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722688 | 1.00 | GRIA2 (0.50) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL5722914 | 1.00 | GRIA2 (0.50) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL5722909 | 1.00 | GRIA2 (0.50) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL5722678 | 0.99 | GRIA2 (0.49) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL5722674 | 0.99 | GRIA2 (0.49) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL5722676 | 0.99 | GRIA2 (0.49) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL4704610 | 0.81 | GRIA2 (0.74) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL5722553 | 0.79 | GRIA1 (0.56) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL5722549 | 0.79 | GRIA1 (0.56) | GRIA2GRIA1GRIA3GRIA4CYP1A2 | |
| SCHEMBL5722655 | 0.78 | GRIA1 (0.55) | GRIA2GRIA1GRIA3GRIA4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097927-B1 | CYANOIMINOQUINOXALINE DERIVATIVES | SHIONOGI & CO (JP) | 2006-07-19 | — | — | EP | disclosed |