⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240170 | 1.00 | — | — | |
| SCHEMBL221055 | 1.00 | — | — | |
| Bromide SCHEMBL7327552 | 0.98 | GLI1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL6976932 | 0.98 | GLI1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL30937515 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL25236164 | 0.98 | GLI1 (0.59) | — | |
| Bromide SCHEMBL7327555 | 0.98 | GLI1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL4316344 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL241228 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL241227 | 0.98 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605407-A2 | METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS | Endevica Bio, Inc. (US) | 2025-08-27 | — | — | EP | claimed |
| WO-2024086381-A2 | METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS | ENDEVICA BIO, INC. (US) | 2024-04-25 | — | — | WO | claimed |
| US-20240025949-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | TREVENA, INC. | 2024-01-25 | — | — | US | claimed |
| CN-116693439-A | Synthesis method of (R) -N-methyl-1- (pyrrolidine-2-yl) methylamine | 南通敏言生物医药科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116606235-A | Synthesis method of (R) - (1-methylpyrrolidine-2-yl) methylamine dihydrochloride | 南通敏言生物医药科技有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-111601798-B | Bisamide sarcomere activating compounds and uses thereof | 美国安进公司 | 2023-08-11 | — | — | CN | claimed |
| CN-110240631-B | Chiral isoindolone cyclopeptide derivative, preparation method and application thereof | 哈尔滨师范大学 | 2023-02-17 | — | — | CN | claimed |
| CN-114436925-A | M-diphenyl phenol ether compound and its preparation method and use | 河北大学 | 2022-05-06 | — | — | CN | claimed |
| CN-110702820-B | HPLC method for separating absinthin A, B | 南京泓纬医药科技有限公司 | 2022-05-03 | — | — | CN | claimed |
| EP-2772476-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | HAMARI CHEMICALS LTD (JP) | 2017-01-11 | — | — | EP | claimed |
| EP-1615921-A2 | PYRIDO 2,3-D PYRIMIDIN-7-CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-01-18 | — | — | EP | claimed |
| WO-2005090344-A1 | NOVEL DICHLORO-PHENYL-PYRIDO [2,3-D] PYRIMIDINE DERIVATES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-29 | — | — | WO | claimed |
| US-20050130984-A1 | Pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents | F. HOFFMANN-LA ROCHE AG (DE) | 2005-06-16 | — | — | US | claimed |
| EP-0929553-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2005-03-16 | — | — | EP | claimed |
| WO-2004085436-A2 | PYRIDO[2,3-D]PYRIMIDIN-7-CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-10-07 | — | — | WO | claimed |
| US-6599902-B2 | For treating or preventing a protein kinase related disorder | SUGEN, INC. | 2003-07-29 | — | — | US | claimed |
| US-6251911-B1 | Pyrimidine derivatives and processes for the preparation thereof | NOVARTIS AG (CH) | 2001-06-26 | — | — | US | claimed |
| EP-0929553-A1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Novartis AG (CH) | 1999-07-21 | — | — | EP | claimed |
| WO-1998014450-A1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 1998-04-09 | — | — | WO | claimed |
| US-5688913-A | OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS | CYTEL CORPORATION (US) | 1997-11-18 | — | — | US | claimed |