SCHEMBL5723643

SCHEMBL5723643

CO[C@@H]1C[C@H](C(=O)Nc2ccc(-c3ccccc3)c(S(N)(=O)=O)c2F)N(C(=O)Nc2ccc(Cl)cc2)C1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 14/20 0.63
KLKB1 P03952 3/20 0.47
CFD P00746 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6597737 0.83 F10 (0.67) F10
SCHEMBL3829980 0.81 F10 (0.87) F10KLKB1
SCHEMBL3833655 0.78 F10 (0.61) F10KLKB1CFD
SCHEMBL4096854 0.78 F10 (0.74) F10KLKB1
SCHEMBL3834625 0.78 F10 (1.00) F10KLKB1
SCHEMBL3828956 0.78 F10 (1.00) F10KLKB1
SCHEMBL3835444 0.78 F10 (1.00) F10KLKB1
SCHEMBL3835301 0.77 F10 (0.80) F10KLKB1
SCHEMBL3830205 0.76 F10 (0.76) F10KLKB1
SCHEMBL5829386 0.76 F10 (0.60) F10KLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465864-B1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE WARNER LAMBERT CO (US) 2006-03-15 EP disclosed