SCHEMBL5723991

SCHEMBL5723991

CO[C@@H]1CC(C(=O)Nc2ccc(-n3cc(Br)ccc3=O)cc2F)N(C(=O)O)C1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3829947 1.00 F10 (0.59) F10
SCHEMBL3830284 0.90 F10 (0.68) F10
SCHEMBL3832110 0.89 F10 (0.60) F10
SCHEMBL3834679 0.88 F10 (0.53) F10
SCHEMBL3828800 0.88 F10 (0.61) F10
SCHEMBL3836239 0.86 F10 (0.57) F10
SCHEMBL3833777 0.84 F10 (0.50) F10
SCHEMBL3835389 0.84 F10 (0.60) F10
SCHEMBL3828590 0.84 F10 (0.67) F10
SCHEMBL3828711 0.84 F10 (0.63) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465864-B1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE WARNER LAMBERT CO (US) 2006-03-15 — — EP disclosed
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