Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724373 | 0.94 | F10 (0.57) | F10KLKB1KCNH2 | |
| SCHEMBL5723857 | 0.91 | F10 (0.62) | F10KLKB1KCNH2 | |
| SCHEMBL3835139 | 0.91 | F10 (0.60) | F10KLKB1KCNH2 | |
| SCHEMBL5723715 | 0.89 | F10 (0.71) | F10KLKB1 | |
| SCHEMBL3828803 | 0.89 | F10 (0.58) | F10KLKB1KCNH2 | |
| SCHEMBL3828805 | 0.89 | F10 (0.58) | F10KLKB1KCNH2 | |
| SCHEMBL3830307 | 0.89 | F10 (0.58) | F10KLKB1KCNH2 | |
| SCHEMBL3830313 | 0.89 | F10 (0.58) | F10KLKB1KCNH2 | |
| SCHEMBL5724447 | 0.89 | F10 (0.51) | F10KLKB1KCNH2 | |
| SCHEMBL3833235 | 0.86 | F10 (0.64) | F10KLKB1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-B1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER LAMBERT CO (US) | 2006-03-15 | — | — | EP | claimed |