SCHEMBL5724322

SCHEMBL5724322

CCOC(=O)OC1CC(C(=O)Nc2ccc(N3CCCCC3=O)cc2F)N(C(=O)Nc2ccc(Cl)cc2)C1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.57
F2 P00734 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5724313 0.93 F10 (0.61) F10F2
SCHEMBL3836042 0.91 F10 (0.63) F10F2
SCHEMBL5723832 0.90 F10 (0.59) F10F2
SCHEMBL3832154 0.89 F10 (0.70) F10F2
SCHEMBL3836109 0.89 F10 (0.70) F10F2
SCHEMBL3848958 0.89 F10 (0.58) F10F2
SCHEMBL3829963 0.89 F10 (0.58) F10F2
SCHEMBL3828317 0.88 F10 (0.59) F10F2
SCHEMBL3829968 0.88 F10 (0.69) F10F2
SCHEMBL3828327 0.87 F10 (0.71) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465864-B1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE WARNER LAMBERT CO (US) 2006-03-15 EP claimed