Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724442 | 0.96 | F10 (0.36) | F10TSHRMAPK1NPSR1IRAK4 | |
| SCHEMBL5724779 | 0.86 | F10 (0.38) | F10RAB9ANPC1 | |
| SCHEMBL5724627 | 0.85 | F10 (0.41) | F10IRAK4RAB9AIRAK1NPC1 | |
| SCHEMBL4270026 | 0.81 | F10 (0.40) | F10IRAK4RAB9AIRAK1NPC1 | |
| SCHEMBL4277535 | 0.81 | CACNB4 (0.42) | F10TSHRMAPK1NPSR1IRAK4 | |
| SCHEMBL4274405 | 0.81 | CACNB4 (0.42) | F10TSHRMAPK1NPSR1IRAK4 | |
| SCHEMBL4274401 | 0.81 | CACNB4 (0.42) | F10TSHRMAPK1NPSR1IRAK4 | |
| SCHEMBL4280035 | 0.79 | NPC1 (0.50) | F10RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL6712441 | 0.79 | NPC1 (0.46) | F10TSHRRAB9ATP53SMN1; SMN2 | |
| SCHEMBL4268742 | 0.79 | CNR1 (0.39) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644334-A1 | ANTITHROMBOTIC ETHERS | Eli Lilly and Company (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004108677-A1 | ANTITHROMBOTIC ETHERS | ELI LILLY AND COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |