Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.68 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833838 | 0.92 | F10 (0.70) | F10KLKB1 | |
| SCHEMBL4110651 | 0.90 | F10 (0.70) | F10KLKB1 | |
| SCHEMBL3828688 | 0.88 | F10 (0.68) | F10KLKB1 | |
| SCHEMBL3833599 | 0.86 | F10 (0.75) | F10KLKB1 | |
| SCHEMBL3830144 | 0.84 | F10 (0.73) | F10KLKB1 | |
| SCHEMBL3834487 | 0.84 | F10 (0.73) | F10KLKB1 | |
| SCHEMBL3828745 | 0.84 | F10 (0.72) | F10KLKB1 | |
| SCHEMBL3834372 | 0.83 | F10 (0.69) | F10KLKB1 | |
| SCHEMBL3830334 | 0.83 | F10 (0.71) | F10KLKB1 | |
| SCHEMBL3828327 | 0.83 | F10 (0.71) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-B1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER LAMBERT CO (US) | 2006-03-15 | — | — | EP | claimed |