SCHEMBL5724901

SCHEMBL5724901

CC(C)(C)[Si](OC1CCN(c2nc(C(N)=O)cs2)C1)(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SCD O00767 2/20 0.54
HRH3 Q9Y5N1 3/20 0.48
PTGER1 P34995 1/20 0.38
SMN1; SMN2 Q16637 7/20 0.37
OGA O60502 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RAB9A P51151 4/20 0.36
NPC1 O15118 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5724202 1.00 SCD (0.54) SCDHRH3PTGER1SMN1; SMN2OGA
SCHEMBL5724380 1.00 SCD (0.54) SCDHRH3PTGER1SMN1; SMN2OGA
SCHEMBL5724879 0.92 PTGER1 (0.45) SCDHRH3PTGER1OGAL3MBTL1
SCHEMBL5724639 0.92 PTGER1 (0.45) SCDHRH3PTGER1OGAL3MBTL1
SCHEMBL5724642 0.92 PTGER1 (0.45) SCDHRH3PTGER1OGAL3MBTL1
SCHEMBL5724070 0.92 SCD (0.48) SCDHRH3PTGER1SMN1; SMN2OGA
SCHEMBL5724547 0.87 OGA (0.41) SCDHRH3SMN1; SMN2OGAL3MBTL1
SCHEMBL5724024 0.87 OGA (0.41) SCDHRH3SMN1; SMN2OGAL3MBTL1
SCHEMBL5724728 0.83 PTGER1 (0.41) SCDPTGER1L3MBTL1
SCHEMBL5724205 0.80 MEN1 (0.40) SCDHRH3PTGER1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed