Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726345 | 0.90 | ESR2 (0.59) | ESR2ESR1 | |
| SCHEMBL5726266 | 0.84 | ESR1 (0.55) | ESR2ESR1 | |
| SCHEMBL5726235 | 0.77 | ESR2 (0.54) | ESR2ESR1 | |
| SCHEMBL5726037 | 0.76 | ESR2 (0.51) | ESR2ESR1 | |
| SCHEMBL5726270 | 0.75 | ESR2 (0.54) | ESR2ESR1 | |
| SCHEMBL5725999 | 0.75 | ESR2 (0.57) | ESR2ESR1 | |
| SCHEMBL5582147 | 0.72 | ESR1 (0.47) | ESR2ESR1 | |
| SCHEMBL5430051 | 0.71 | ESR2 (0.69) | ESR2ESR1 | |
| SCHEMBL5339578 | 0.71 | ESR2 (0.65) | ESR2ESR1 | |
| SCHEMBL5336245 | 0.69 | ESR2 (0.54) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339683-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-1339683-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1339683-A2 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002041835-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2002-05-30 | — | — | WO | disclosed |