SCHEMBL5725940

SCHEMBL5725940

O=C(O)C(=CC=Cc1ccccc1)CCCO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.56
MCL1 Q07820 2/20 0.42
MAOB P27338 1/20 0.41
ALDH1A1 P00352 5/20 0.40
LMNA P02545 4/20 0.40
HDAC3 O15379 3/20 0.40
HDAC4 P56524 3/20 0.40
HDAC1 Q13547 3/20 0.40
HDAC7 Q8WUI4 3/20 0.40
HDAC2 Q92769 3/20 0.40
HDAC10 Q969S8 3/20 0.40
HDAC11 Q96DB2 3/20 0.40
HDAC8 Q9BY41 3/20 0.40
HDAC6 Q9UBN7 3/20 0.40
HDAC9 Q9UKV0 3/20 0.40
HDAC5 Q9UQL6 3/20 0.40
CYP2C9 P11712 2/20 0.40
CYP3A4 P08684 1/20 0.40
HAO1 Q9UJM8 1/20 0.40
TRPA1 O75762 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7589578 0.90 GRIK1 (0.59) GRIK1MCL1MAOBALDH1A1LMNA
SCHEMBL23934240 0.86 GRIK1 (0.55) GRIK1MCL1ALDH1A1LMNAHDAC3
SCHEMBL375312 0.86 GRIK1 (0.55) GRIK1MCL1ALDH1A1LMNAHDAC3
SCHEMBL393958 0.84 GRIK1 (0.54) GRIK1ALDH1A1LMNAHDAC3ALOX5
SCHEMBL7780529 0.83 TDP1 (0.52) GRIK1ALDH1A1LMNAHDAC3KDM4E
SCHEMBL11445983 0.83 TDP1 (0.52) GRIK1ALDH1A1LMNAHDAC3KDM4E
SCHEMBL905410 0.83 TDP1 (0.52) GRIK1ALDH1A1LMNAHDAC3KDM4E
SCHEMBL10904990 0.83 TDP1 (0.52) GRIK1ALDH1A1LMNAHDAC3KDM4E
SCHEMBL7107526 0.83 TDP1 (0.52) GRIK1ALDH1A1LMNAHDAC3KDM4E
SCHEMBL5498940 0.83 GRIK1 (0.52) GRIK1MCL1HDAC6CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191590-B1 SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES QUANTUMDX GROUP LTD (GB) 2024-02-21 EP disclosed
US-10792640-B2 Sorbent material for separating bio-macromolecules QUANTUMDX GROUP LIMITED (GB) 2020-10-06 US disclosed
US-20170282154-A1 SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES QUANTUMDX GROUP LIMITED (GB) 2017-10-05 US disclosed
EP-1691238-A2 Coating compositions for use with an overcoated photoresist Rohm and Haas Electronic Materials, L.L.C. (US) 2006-08-16 EP disclosed
EP-0366566-B1 Reference electrodes TERUMO CORP (JP) 1998-06-03 EP disclosed
US-5213675-A Lamination films covering surfaces of electroconductive substrates and silver halide films TERUMO KABUSHIKI KAISHA (JP) 1993-05-25 US disclosed
US-5066383-A REFERENCE ELECTRODE, ION SENSOR AND METHOD OF MANUFACTURING THE SAME TERUMO KABUSHIKI KAISHA (JP) 1991-11-19 US disclosed
EP-0366566-A2 Reference electrode, ion sensor and method of manufacturing the same TERUMO KABUSHIKI KAISHA (JP) 1990-05-02 EP disclosed