Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726188 | 0.74 | — | — | |
| SCHEMBL5726121 | 0.70 | NPC1 (0.31) | — | |
| SCHEMBL5726418 | 0.70 | BUB1 (0.34) | — | |
| SCHEMBL5432860 | 0.65 | ESR2 (0.67) | ESR2 | |
| SCHEMBL5725670 | 0.64 | CYP19A1 (0.32) | ESR2 | |
| SCHEMBL5432545 | 0.64 | ESR2 (0.67) | ESR2 | |
| SCHEMBL5432124 | 0.63 | ESR2 (0.67) | ESR2 | |
| SCHEMBL2419168 | 0.63 | UTS2R (0.37) | ESR2 | |
| SCHEMBL2418588 | 0.62 | NOTUM (0.33) | ESR2 | |
| SCHEMBL5428093 | 0.62 | ESR1 (0.68) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339683-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-1339683-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1339683-A2 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002041835-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2002-05-30 | — | — | WO | disclosed |