Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5441515 | 0.84 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL5421745 | 0.74 | ESR2 (1.00) | ESR1ESR2 | |
| SCHEMBL5727164 | 0.72 | ESR1 (0.59) | ESR1ESR2 | |
| SCHEMBL5421283 | 0.72 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL5425066 | 0.71 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL5428232 | 0.70 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL5428947 | 0.69 | ESR2 (1.00) | ESR1ESR2 | |
| SCHEMBL5582295 | 0.65 | ESR1 (0.79) | ESR1ESR2 | |
| SCHEMBL1658311 | 0.65 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL5424359 | 0.64 | ESR2 (1.00) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339683-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-1339683-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1339683-A2 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002041835-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2002-05-30 | — | — | WO | disclosed |