Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.63 |
| ▸ | PPARA | Q07869 | 19/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727106 | 1.00 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL5424349 | 0.94 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL5424352 | 0.94 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL5421831 | 0.93 | PPARA (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5727708 | 0.93 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL5429733 | 0.93 | PPARA (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5427997 | 0.93 | PPARA (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5727704 | 0.93 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL5913743 | 0.93 | PPARG (0.71) | PPARGPPARA | |
| SCHEMBL5913737 | 0.93 | PPARG (0.71) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1502590-B1 | Heterocyclic oxime derivatives, process for their preparation and use thereof in the treatment of type II diabetes | SERVIER LAB (FR) | 2006-12-20 | — | — | EP | claimed |
| EP-1502590-A1 | Heterocyclic oxime derivatives, process for their preparation and use thereof in the treatment of type II diabetes | Les Laboratoires Servier (FR) | 2005-02-02 | — | — | EP | claimed |
| EP-1502590-B1 | Heterocyclic oxime derivatives, process for their preparation and use thereof in the treatment of type II diabetes | SERVIER LAB (FR) | 2006-12-20 | — | — | EP | disclosed |
| EP-1729767-A1 | COMBINATION OF A HETEROCYCLIC COMPOUND AND AN ANTIOXIDANT AND USE THEREOF FOR TREATING OBESITY | Les Laboratoires Servier (FR) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005099694-A1 | COMBINATION OF A HETEROCYCLIC COMPOUND AND AN ANTIOXIDANT AND USE THEREOF FOR TREATING OBESITY | LES LABORATOIRES SERVIER (FR) | 2005-10-27 | — | — | WO | disclosed |
| EP-1502590-A1 | Heterocyclic oxime derivatives, process for their preparation and use thereof in the treatment of type II diabetes | Les Laboratoires Servier (FR) | 2005-02-02 | — | — | EP | disclosed |