Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.79 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.70 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.70 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.70 |
| ▸ | ACE | P12821 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
| ▸ | FAP | Q12884 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285933 | 0.92 | DPP4 (0.80) | DPP4DPP8DPP9DPP7ACE | |
| Hydrochloric Acid SCHEMBL2553853 | 0.91 | DPP4 (0.79) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL15604142 | 0.91 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL4105920 | 0.91 | DPP4 (0.78) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL30535992 | 0.91 | DPP4 (0.78) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL2783499 | 0.91 | DPP4 (0.78) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL2555447 | 0.90 | DPP4 (0.83) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL12286052 | 0.90 | DPP4 (0.77) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL2384182 | 0.89 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL15282250 | 0.89 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2600888-A2 | NOVEL COMPOUNDS AS DPP-IV INHIBITORS AND PROCESS FOR PREPARATION THEREOF | Cadila Pharmaceuticals Ltd. (IN) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017391-A2 | NOVEL COMPOUNDS AS DPP-IV INHIBITORS AND PROCESS FOR PREPARATION THEREOF | CADILA PHARMACEUTICALS LIMITED (IN) | 2012-02-09 | — | — | WO | disclosed |