SCHEMBL5727888

SCHEMBL5727888

CC(C)(C)SC(=O)[C@@H](N)CS

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 2/20 0.44
▸ SLC7A11 Q9UPY5 1/20 0.44
▸ ENPEP Q07075 6/20 0.32
▸ CPB2 Q96IY4 3/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ NOS1 P29475 1/20 0.31
▸ ANPEP P15144 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2941633 0.74 PTGS1 (0.55) PTGS1SLC7A11ENPEPCPB2ANPEP
SCHEMBL456395 0.74 PTGS1 (0.55) PTGS1SLC7A11ENPEPCPB2ANPEP
SCHEMBL28547750 0.74 PTGS1 (0.55) PTGS1SLC7A11ENPEPCPB2ANPEP
SCHEMBL2941639 0.74 PTGS1 (0.55) PTGS1SLC7A11ENPEPCPB2ANPEP
SCHEMBL3165379 0.72 PTGS1 (0.43) PTGS1SLC7A11ENPEPALDH1A1MAPT
SCHEMBL28440494 0.72 — —
SCHEMBL31130601 0.72 — —
SCHEMBL2941641 0.72 — —
SCHEMBL359013 0.72 — —
SCHEMBL27589324 0.71 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003822-A SG3C bromobenzyl ether derivative, preparation method and application 江苏省原子医学研究所 2023-11-07 — — CN claimed
CN-117003815-A SG2C bromobenzyl ether derivative, preparation method and application 江苏省原子医学研究所 2023-11-07 — — CN claimed
EP-1679318-A1 Process for folding chemically synthesized polypeptides RMF DICTAGENE S.A. (CH) 2006-07-12 — — EP claimed
EP-1337549-B1 PROCESS FOR FOLDING CHEMICALLY SYNTHESIZED POLYPEPTIDES RMF DICTAGENE SA (CH) 2006-04-05 — — EP claimed
US-20050239162-A1 Process for folding chemically synthesized polypeptides RMF DICTAGENE S.A. (CH) 2005-10-27 — — US claimed
EP-1337549-A2 PROCESS FOR FOLDING CHEMICALLY SYNTHESIZED POLYPEPTIDES RMF DICTAGENE S.A. (CH) 2003-08-27 — — EP claimed
WO-2002050099-A2 PROCESS FOR FOLDING CHEMICALLY SYNTHESIZED POLYPEPTIDES RMF DICTAGENE S.A. (CH) 2002-06-27 — — WO claimed
US-20020082384-A1 Process for folding chemically synthesized polypeptides RMF DICTAGENE S.A. (CH) 2002-06-27 — — US claimed
EP-3953367-B1 VERSATILE PEPTIDE AND PROTEIN MACROCYCLIZATION AND MULTIMERIZATION WITH DIELS-ALDER CYCLOADDITIONS UNIV CHICAGO (US) 2026-02-11 — — EP disclosed
EP-4600411-A2 VERSATILE PEPTIDE AND PROTEIN MACROCYCLIZATION AND MULTIMERIZATION WITH DIELS-ALDER CYCLOADDITIONS The University of Chicago (US) 2025-08-13 — — EP disclosed
US-20250122240-A1 Versatile Peptide and Protein Macrocyclization and Multimerization with Diels-Alder Cycloadditions THE UNIVERSITY OF CHICAGO (US) 2025-04-17 — — US disclosed
US-12209143-B2 Versatile peptide and protein macrocyclization and multimerization with diels-alder cycloadditions THE UNIVERSITY OF CHICAGO (US) 2025-01-28 — — US disclosed
WO-2025006976-A2 MRNA DISPLAY LIBRARIES AND METHODS OF USE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2025-01-02 — — WO disclosed
CN-117003815-A SG2C bromobenzyl ether derivative, preparation method and application 江苏省原子医学研究所 2023-11-07 — — CN disclosed
EP-1679318-A1 Process for folding chemically synthesized polypeptides RMF DICTAGENE S.A. (CH) 2006-07-12 — — EP disclosed
EP-1337549-B1 PROCESS FOR FOLDING CHEMICALLY SYNTHESIZED POLYPEPTIDES RMF DICTAGENE SA (CH) 2006-04-05 — — EP disclosed
US-20050239162-A1 Process for folding chemically synthesized polypeptides RMF DICTAGENE S.A. (CH) 2005-10-27 — — US disclosed
EP-1337549-A2 PROCESS FOR FOLDING CHEMICALLY SYNTHESIZED POLYPEPTIDES RMF DICTAGENE S.A. (CH) 2003-08-27 — — EP disclosed
WO-2002050099-A2 PROCESS FOR FOLDING CHEMICALLY SYNTHESIZED POLYPEPTIDES RMF DICTAGENE S.A. (CH) 2002-06-27 — — WO disclosed
US-20020082384-A1 Process for folding chemically synthesized polypeptides RMF DICTAGENE S.A. (CH) 2002-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122240-A1 Versatile Peptide and Protein Macrocyclization and Multimerization with Diels-Alder Cycloadditions SPPL2B, MAX, DNPEP PTGS1 4447/4885SLC7A11 2830/4885ENPEP 33/4885
US-12209143-B2 Versatile peptide and protein macrocyclization and multimerization with diels-alder cycloadditions SPPL2B, MAX, DNPEP PTGS1 4447/4885SLC7A11 2830/4885ENPEP 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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