Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.91 |
| ▸ | CASP1 | P29466 | 1/20 | 0.91 |
| ▸ | CASP7 | P55210 | 1/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351116 | 0.95 | — | — | |
| SCHEMBL6187 | 0.95 | — | — | |
| SCHEMBL5167521 | 0.95 | CYP3A4 (1.00) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL1991061 | 0.91 | — | — | |
| SCHEMBL22003326 | 0.91 | CYP3A4 (0.91) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL7547107 | 0.91 | CYP3A4 (0.91) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Fluoride SCHEMBL20497200 | 0.91 | CYP3A4 (0.91) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL22833905 | 0.91 | — | — | |
| Methane SCHEMBL21408528 | 0.91 | — | — | |
| SCHEMBL1674112 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875583-B1 | Primers and kits for the detection of Chlamydia trachomatis | HOFFMANN LA ROCHE (CH) | 2006-11-15 | — | — | EP | disclosed |
| EP-0420260-B1 | METHOD AND KIT FOR DETECTING A TARGET NUCLEIC ACID USING A CAPTURE PROBE BOUND TO A POLYSTYRENE SUPPORT VIA AN INTERMEDIARY PROTEIN. | HOFFMANN LA ROCHE (CH) | 1999-12-08 | — | — | EP | disclosed |
| EP-0875583-A2 | Primers and kits for the detection of Chlamydia trachomatis | F. Hoffmann-La Roche AG (CH) | 1998-11-04 | — | — | EP | disclosed |
| US-5232829-A | Diagnostic kit containing oligonucleotide primer/probe bound to microtiter plate having a plurality of wells | HOFFMANN-LA ROCHE INC. (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0420260-A2 | Biotin-labelled DNA by polymerase chain reaction and detection thereof | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1991-04-03 | — | — | EP | disclosed |
| EP-0292128-A1 | Improved DNA probes | TAMIR BIOTECHNOLOGY LTD (IL) | 1988-11-23 | — | — | EP | disclosed |