Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 9/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728317 | 1.00 | SLC2A1 (0.50) | SLC2A1KCNH2PDGFRB | |
| SCHEMBL5728313 | 1.00 | SLC2A1 (0.50) | SLC2A1KCNH2PDGFRB | |
| SCHEMBL5726126 | 0.89 | SLC2A1 (0.50) | SLC2A1KCNH2 | |
| SCHEMBL5726129 | 0.89 | SLC2A1 (0.50) | SLC2A1KCNH2 | |
| SCHEMBL5726122 | 0.89 | SLC2A1 (0.50) | SLC2A1KCNH2 | |
| SCHEMBL5739124 | 0.83 | SLC2A1 (0.62) | SLC2A1KCNH2 | |
| SCHEMBL5739137 | 0.83 | SLC2A1 (0.62) | SLC2A1KCNH2 | |
| SCHEMBL5739145 | 0.83 | SLC2A1 (0.62) | SLC2A1KCNH2 | |
| SCHEMBL5927692 | 0.82 | SLC2A1 (0.59) | SLC2A1KCNH2 | |
| SCHEMBL5725985 | 0.79 | SLC2A1 (0.56) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719770-A2 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |
| EP-1320529-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-05-24 | — | — | EP | disclosed |