Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.48 |
| ▸ | LSS | P48449 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5728956 | 0.99 | F10 (0.47) | F10LSSTPSAB1ATMCHRM1 | |
| SCHEMBL5730605 | 0.90 | LSS (0.58) | F10LSSCHRM1 | |
| SCHEMBL5729098 | 0.89 | F10 (0.61) | F10 | |
| Hydrochloric Acid SCHEMBL5729796 | 0.88 | F10 (0.61) | F10 | |
| SCHEMBL8118785 | 0.83 | F10 (0.48) | F10LSSTPSAB1ATMCHRM1 | |
| Hydrochloric Acid SCHEMBL7050686 | 0.83 | F10 (0.47) | F10LSSTPSAB1ATMCHRM1 | |
| SCHEMBL6797988 | 0.82 | TP53 (0.48) | F10LSSCHRM1 | |
| SCHEMBL5729187 | 0.81 | F10 (0.46) | F10LSSATM | |
| SCHEMBL5729816 | 0.81 | F10 (0.61) | F10 | |
| Hydrochloric Acid SCHEMBL5729549 | 0.80 | F10 (0.45) | F10LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | claimed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | claimed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | claimed |
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |