Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5729622 | 0.99 | F10 (0.51) | F10F2PLATKLKB1KDM4E | |
| SCHEMBL5729098 | 0.89 | F10 (0.61) | F10 | |
| Hydrochloric Acid SCHEMBL5729796 | 0.88 | F10 (0.61) | F10 | |
| SCHEMBL5729588 | 0.84 | F10 (0.51) | F10F2PLATKLKB1KDM4E | |
| SCHEMBL5729414 | 0.84 | F10 (0.51) | F10SMN1; SMN2HTT | |
| SCHEMBL5728845 | 0.83 | F10 (0.58) | F10F2PLATKLKB1KDM4E | |
| SCHEMBL5731177 | 0.83 | F10 (0.49) | F10F2PLATKLKB1 | |
| SCHEMBL5729659 | 0.83 | F10 (0.43) | F10F2KDM4ESMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5728947 | 0.83 | F10 (0.57) | F10F2PLATKLKB1KDM4E | |
| SCHEMBL5729785 | 0.82 | F10 (0.50) | F10F2PLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |