SCHEMBL5729344

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5729698	0.92	CHEK2 (0.45)	CHEK2SSTR2CHEK1ESR1ESR2
	SCHEMBL5729282	0.89	CHEK2 (0.49)	CHEK2SSTR2CHEK1ESR1ESR2
	SCHEMBL6304487	0.87	CHEK2 (0.46)	CHEK2SSTR2CHEK1ESR1ESR2
	SCHEMBL5729507	0.86	CHEK2 (0.46)	CHEK2SSTR2CHEK1ESR1ESR2
	SCHEMBL5729625	0.86	CHEK2 (0.46)	CHEK2SSTR2CHEK1ESR1ESR2
	SCHEMBL5731064	0.86	CHEK2 (0.45)	CHEK2CHEK1ESR1ESR2MEN1
	SCHEMBL5729408	0.86	ESR1 (0.43)	CHEK2SSTR2CHEK1ESR1ESR2
	SCHEMBL5729349	0.83	S1PR1 (0.33)	ESR1ESR2SLC6A2SLC6A4SLC6A3
	SCHEMBL5729040	0.83	CHEK2 (0.48)	CHEK2SSTR2CHEK1ESR1ESR2
	SCHEMBL5729341	0.82	ESR1 (0.55)	ESR1ESR2MEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.