Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5729057 | 0.87 | F10 (0.39) | F10CHRM1 | |
| SCHEMBL5729011 | 0.83 | F10 (0.39) | F10CYP17A1CYP21A2CYP11B1CHRM1 | |
| SCHEMBL6895563 | 0.83 | F10 (0.38) | F10CYP17A1CYP21A2CYP11B1 | |
| Hydrochloric Acid SCHEMBL6893743 | 0.82 | F10 (0.38) | F10CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL5729054 | 0.81 | LSS (0.36) | F10 | |
| Hydrochloric Acid SCHEMBL5730230 | 0.80 | LSS (0.36) | F10 | |
| SCHEMBL5729075 | 0.78 | F10 (0.35) | F10CYP17A1CYP21A2CYP11B1CHRM1 | |
| SCHEMBL6895637 | 0.76 | F10 (0.37) | F10CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL6895943 | 0.76 | F10 (0.40) | F10CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL5729150 | 0.74 | LSS (0.38) | F10CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |