Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 12/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729654 | 0.99 | NPY1R (0.78) | NPY1RRAB9ACRHR1ALDH1A1HPGD | |
| SCHEMBL7043574 | 0.92 | NPY1R (0.80) | NPY1RCRHR1ALDH1A1HPGDUSP2 | |
| SCHEMBL1594098 | 0.88 | NPY1R (0.65) | NPY1RRAB9ACRHR1ALDH1A1HPGD | |
| SCHEMBL5729134 | 0.86 | NPY1R (0.85) | NPY1RRAB9ACRHR1ALDH1A1HPGD | |
| SCHEMBL5728933 | 0.85 | NPY1R (0.83) | NPY1RRAB9ACRHR1ALDH1A1HPGD | |
| SCHEMBL5728776 | 0.84 | NPY1R (0.85) | NPY1RRAB9ACRHR1ALDH1A1HPGD | |
| SCHEMBL5729288 | 0.83 | NPY1R (0.73) | NPY1RRAB9ACRHR1ALDH1A1HPGD | |
| SCHEMBL7043079 | 0.83 | NPY1R (0.77) | NPY1RCRHR1ALDH1A1HPGDUSP2 | |
| Hydrochloric Acid SCHEMBL7042696 | 0.82 | NPY1R (0.76) | NPY1RCRHR1ALDH1A1HPGDUSP2 | |
| SCHEMBL5730324 | 0.82 | NPY1R (0.71) | NPY1RRAB9ACRHR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218381-B1 | AMINO SUBSTITUTED PYRAZOLO¬1,5-a|-1,5-PYRIMIDINES AND PYRAZOLO¬1,5-a|-1,3,5-TRIAZINES | NEUROGEN CORP (US) | 2006-12-06 | — | — | EP | claimed |
| US-6476038-B1 | Amino substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines | NEUROGEN CORPORATION | 2002-11-05 | — | — | US | claimed |