Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | FPR3 | P25089 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729612 | 1.00 | P2RY12 (0.72) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| SCHEMBL10074060 | 0.86 | P2RY12 (0.79) | P2RY12CYP2C9 | |
| SCHEMBL5729536 | 0.84 | P2RY12 (0.83) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| SCHEMBL7000932 | 0.84 | P2RY12 (1.00) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| SCHEMBL5115747 | 0.84 | P2RY12 (0.62) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| SCHEMBL5729485 | 0.83 | P2RY12 (1.00) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| SCHEMBL6623324 | 0.83 | P2RY12 (0.79) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| SCHEMBL7482538 | 0.83 | P2RY12 (0.84) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| SCHEMBL2065338 | 0.83 | P2RY12 (1.00) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| SCHEMBL10074052 | 0.83 | P2RY12 (0.76) | P2RY12CYP2C9PGRADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335919-B1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2006-11-15 | — | — | EP | disclosed |
| US-7034032-B2 | Cyclopentan-2-ol-1-yl-[1,2,3]triazolo[4,5-D]pyrimidine compounds | ASTRAZENECA AB (SE) | 2006-04-25 | — | — | US | disclosed |
| US-20040023988-A1 | Novel compounds | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023988-A1 | Novel compounds | DPYD, TYMP, TYMS | P2RY12 132/4885CYP2C9 578/4885PGR 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.