Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.40 |
| ▸ | PPARA | Q07869 | 15/20 | 0.40 |
| ▸ | PPARD | Q03181 | 8/20 | 0.36 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737959 | 0.93 | PPARG (0.45) | PPARGPPARAPPARD | |
| SCHEMBL4887411 | 0.84 | PPARG (0.40) | PPARGPPARAPPARDCSF3R | |
| SCHEMBL4887413 | 0.81 | PPARG (0.44) | PPARGPPARAPPARDCSF3R | |
| SCHEMBL4889108 | 0.81 | PPARG (0.56) | PPARGPPARAPPARDCSF3R | |
| SCHEMBL4896200 | 0.80 | PPARG (0.61) | PPARGPPARAPPARD | |
| SCHEMBL4894563 | 0.77 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL4897388 | 0.77 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL4894571 | 0.74 | PPARG (0.51) | PPARGPPARAPPARDCSF3R | |
| SCHEMBL4897375 | 0.74 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL4894333 | 0.74 | PPARG (0.65) | PPARGPPARAPPARDCSF3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |