Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.45 |
| ▸ | PPARA | Q07869 | 16/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729663 | 0.81 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL5731134 | 0.80 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL5730294 | 0.79 | PPARG (0.52) | PPARGPPARAMAPT | |
| SCHEMBL4895127 | 0.78 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL6633220 | 0.77 | PPARG (0.44) | PPARGPPARARARARARBRARG | |
| SCHEMBL4893594 | 0.76 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL5729457 | 0.76 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL5729994 | 0.74 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL5731023 | 0.73 | ADORA2A (0.37) | PPARGPPARA | |
| SCHEMBL4896410 | 0.72 | PPARG (0.38) | PPARGPPARAMAPTRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |